Endocrine Abstracts

Background: Non-islet-cell tumour hypoglycaemia (NICTH) is a rare paraneoplastic syndrome caused by an extra pancreatic tumour(1). Solitary fibrous tumour (SFT), amongst other tumours, is one of the rare causes of NICTH. We report a case of NICTH who presented with recurrent hypoglycaemias and was identified to have a fibrous tumour as part of the work up for his symptomatic hypoglycaemias.Case Summary: A 75-year male had presented to the emergency depar...

Introduction: Thyroid dysfunction in pregnancy is not uncommon (1). Early recognition and intervention are essential to avoid any adverse pregnancy outcomes however caution must be exercised while interpreting the thyroid functions during pregnancy to avoid any unnecessary treatment.Case report: 32-year female with was referred to the combined antenatal clinic for review following an abnormal thyroid function tests during pregnancy. She had no known medi...

Case History: A female, aged eighty-three was admitted for an elective urology stent procedure. She had a background history of a non-functioning pituitary adenoma diagnosed 3 weeks before admission. This was found after investigation for headache and diplopia. The pituitary lesion was described as 18 × 17 × 14 mm in size and mixed solid/cystic in nature. There was no chiasmal compression. During that admission her case was discussed with neurosurgery and it was felt...

Dopamine agonists can falsely elevate plasma and urinary metanephrines, thus making the diagnosis of pheochromocytomas in patients taking these medications challenging. We present the case of an 80-year-old female care home resident with a background of hypertension, Parkinson’s disease (PD), dementia and pernicious anaemia. She presented with weight loss, unilateral leg swelling and abdominal distension. A computed tomography (CT) showed a 5.6 cm heterogeneously enhancin...

Alemtuzumab is a monoclonal antibody used in the treatment of relapsing-remitting multiple sclerosis (RRMS). Thyroid dysfunction is a common side effect. Alemtuzumab induced Graves’ disease (AIGD) is notable for its fluctuating and unpredictable course. We present the case of two women with RRMS who required total thyroidectomy to manage AIGD and were followed up in our antenatal endocrine clinic during their pregnancy. The first patient is a 31-year-old lady who develope...

Case history: A 41 year old female was admitted following development of severe hypertension (226/146 mmHg), complicated by heart failure and acute kidney injury. She otherwise had no relevant past medical history. On clinical examination she was obese (BMI 51.94 kg/m2). As part of her cardiac investigations, she underwent a cardiac magnetic resonance imaging (MRI) which detected a 3 cm right sided adrenal nodule. An adrenal biochemical screen identified an elevated...